Bone specific alkaline phosphatase test Maharashtra

BONE SPECIFIC ALKALINE PHOSPHATASE

DESCRIPTION – bone specific alkaline phosphatase is used to diagnose and assess the severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover. The test can monitor efficacy of anti-resorptive therapies including post-menopausal osteoporosis treatment

METHODOLOGY – quantitative chemiluminiscent immunoassay

TURN AROUND TIME – within 24 hours

PATIENT PREPARATION –

COLLECT – serum separator tube or green (sodium heparin)

SPECIMEN PREPARATION – transfer 1 ml of serum or plasma to transport tube

STORAGE/TRANSPORT TEMPERATURE – critical frozen

STABILITY – ambient: 2 hours; refrigerated: 48 hours; frozen: 2 months

UNACCEPTABLE CONDITION – urine and grossly hemolyzed specimens

SPECIAL INSTRUCTIONS – clinical history is mandatory