TPMT Genotyping TPMT*1 / *2 / *3A /*3B / *3C Blood

DESCRIPTION – TPMT genotype is an alternative test to TPMT enzyme activity level is a genetic test that can identify genetic variations in the TPMT gene. This genetic test identifies individual genetic differences associated with risk for thio-purine toxicity. Each person has two copies of the TPMT gene

METHODOLOGY – polymerase chain reaction (PCR)

TURN AROUND TIME – 8 days

PATIENT PREPARATION –

COLLECT – lavender (EDTA), pink (potassium EDTA), yellow (ACD solution A or B)

SPECIMEN PREPARATION – transport 3 ml whole blood

STORAGE/TRANSPORT TEMPERATURE – refrigerated

STABILITY – ambient: 72 hours; refrigerated: 1 week; frozen: 1 month

UNACCEPTABLE CONDITION – plasma or serum. Frozen specimens

MRP – 4500.00

SPECIAL INSTRUCTIONS – clinical history is mandatory