Description- This is used in subtyping of blastic leukemia. It is positive in all acute lymphoblastic leukemia (ALL) except Burkitt and B-cell FAB L-3; and in lymphoblastic crisis of chromic myelogenous leukemia (CML-BC-ALL) and lymphoblastic lymphoma. Some nonlymphocytic leukemias also express positivity but there is less intensity and greater variability.
TAT: 3-5 days
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable