What is a hypereosinophilic syndrome?

Hypereosinophilic syndrome (HES) is a rare disease characterized by an overproduction of eosinophils, a type of white blood cell that plays a crucial role in the body's immune system. Eosinophils typically make up less than 5 percent of the total white blood cell count, but in HES, these cells can make up as much as 50 percent or more.

HES is classified as a myeloproliferative disorder, which means that it is caused by a problem with the bone marrow, where blood cells are produced. In many cases, the exact cause of HES is unknown, but it is believed to be related to a genetic mutation that causes the bone marrow to produce too many eosinophils.

Symptoms of HES can vary widely depending on the severity of the disease and which organs are affected. Common symptoms include fever, fatigue, weight loss, skin rashes, and swelling of the limbs. In some cases, HES can lead to serious complications such as heart damage, lung damage, or neurological problems.

Diagnosis of HES typically involves a combination of blood tests, imaging tests, and tissue biopsies. Treatment may involve medications to reduce the number of eosinophils in the blood or to manage symptoms such as inflammation. In severe cases, bone marrow transplantation may be necessary.

Because HES is a rare disease, it is important for patients to see a healthcare provider with expertise in diagnosing and treating this condition. Physicians who specialize in hematology or oncology may be best equipped to manage HES. It is also important for patients to communicate any and all symptoms to their healthcare provider, as early diagnosis and treatment can help prevent complications and improve outcomes.

In conclusion, the hypereosinophilic syndrome is a rare but serious condition that affects the immune system by causing an overproduction of eosinophils. The disease is classified as a myeloproliferative disorder and can lead to a range of symptoms and complications. A proper diagnosis and treatment plan are crucial for managing HES, and patients should seek out a healthcare provider with experience in this area.
How much does a hypereosinophilic syndrome test cost in ?

Hypereosinophilic syndrome is a rare hematological disorder that can cause damage to multiple organs. The diagnosis of this disease involves several laboratory tests, including complete blood count, serum chemistry, and a bone marrow biopsy. The cost of a hypereosinophilic syndrome test can vary depending on the type of test and the location of the laboratory where it is performed.

In , the cost of a complete blood count (CBC) test, which is an essential test for the diagnosis of hypereosinophilic syndrome, can range from INR 200 to INR 1000, depending on the laboratory and the quality of the test. A serum chemistry test, which measures the levels of various chemicals in the blood, can cost between INR 500 to INR 2500, depending on the type of test and the laboratory.

A bone marrow biopsy, which is the most definitive test for hypereosinophilic syndrome, can cost between INR 5000 to INR 15000 in , depending on the hospital and the specialist who performs the test. In addition to the cost of the test, there may be additional charges for consultation and follow-up visits with the doctor.

It is important to note that the cost of a hypereosinophilic syndrome test should not be the only factor considered when deciding where to get the test done. The quality of the laboratory, the expertise of the healthcare professional, and the availability of follow-up care are all important factors to consider. It is crucial to ensure that the laboratory and healthcare professionals are accredited and have a good reputation. Additionally, it is important to discuss any concerns or questions with the healthcare professional before proceeding with the test.

In conclusion, the cost of a hypereosinophilic syndrome test can vary depending on the type of test and the location of the laboratory. In , the cost of a complete blood count test can range from INR 200 to INR 1000, a serum chemistry test can cost between INR 500 to INR 2500, and a bone marrow biopsy can cost between INR 5000 to INR 15000. However, it is important to prioritize the quality and expertise of the laboratory and healthcare professional when choosing where to get the test done.

What is the average waiting time for a hypereosinophilic syndrome test in ?

Hypereosinophilic syndrome (HES) is a rare disorder characterized by a high level of eosinophils in the blood. This condition can cause damage to organs such as the heart, lungs, liver, and digestive system. Individuals who exhibit HES symptoms must undergo a series of tests for proper diagnosis and treatment.

In , the average waiting time for a hypereosinophilic syndrome test varies depending on several factors, including the hospital or clinic's location, the availability of the necessary equipment and medical professionals, and the workload of the facility. On average, patients may have to wait anywhere from a few days to a few weeks to receive their HES test results.

It is important to note that individuals experiencing HES symptoms should seek medical attention promptly. Delaying diagnosis and treatment can lead to severe complications and even death.

To ensure timely diagnosis and treatment, patients can consider visiting a healthcare facility that specializes in diagnosing and treating rare disorders like HES. Additionally, scheduling an appointment in advance and inquiring about wait times can help patients plan accordingly and minimize any potential delays.

In conclusion, the average waiting time for a hypereosinophilic syndrome test in may vary based on several factors. However, patients must prioritize seeking medical attention promptly to prevent any potential complications associated with this rare condition.

Are the results of a hypereosinophilic syndrome test available quickly in ?

Hypereosinophilic syndrome (HES) is a rare disorder characterized by an increase in the number of eosinophils in the blood. The diagnosis of HES involves a series of tests, including blood tests, imaging studies, and bone marrow biopsy, which can take time to perform and analyze.

In , the availability of HES testing may vary depending on the hospital or laboratory. However, most diagnostic centers should be able to perform a complete blood count (CBC) with differential, which can help identify an abnormal increase in eosinophils in the blood.

The results of a CBC test are typically available within a few hours to a day, depending on the testing facility. However, it is important to note that a CBC test alone is not enough to diagnose HES. Further testing, such as imaging studies and bone marrow biopsy, may be necessary to confirm the diagnosis.

If you suspect that you may have HES or have been referred for testing by your doctor, it is essential to consult a qualified healthcare provider in who can guide you through the diagnostic process and provide appropriate treatment. They can also advise you on the availability of HES testing in your area and the expected turnaround time for test results.

DESCRIPTION – this syndrome occurs due to the high number of eosinophils
COMPONENT – FGFR1
CLINICAL UTILITY – FGFR1 rearrangement, PDGFRA/FIP1LIA fusion, PDGFRB rearrangement, CBFB/INV by FISH
METHODOLOGY – fluorescence in situ hybridization (FISH)
TURN-AROUND TIME – 12 days
PATIENT PREPARATION –
COLLECT – non diluted bone marrow aspirate or sodium heparin
SPECIMEN PREPARATION – 3-4 ml bone marrow or peripheral blood in green top or lavender top tube
STORAGE/TRANSPORT TEMPERATURE – 2-8 degrees C (with cold pack) and transport within 72 hours
STABILITY – ambient: 48 hours; refrigerated: 48 hours
UNACCEPTABLE CONDITIONS – clotted specimens
MRP – 16000.00
SPECIAL INSTRUCTIONS – clinical history is mandatory