DESCRIPTION – HER2 stands for human epidermal growth factor receptor 2. HER2 gene is present on each breast cell. Due to the HER2 gene mutation, there is a production of too much HER2 protein causing the development of tumor in breast.
CLINICAL UTILITY –
Used for the detection of breast cancer
Sometimes used for checking weather cancer is responding to the treatment
METHODOLOGY – fluorescence in situ hybridization (FISH)
TURN AROUND TIME – 5 days
PATIENT PREPARATION –
COLLECT – tumor tissue
SPECIMEN PREPARATION – formalin fixed paraffin embedded tissue block. Leave it for 6-72 hours. Protect it from excessive heat
STORAGE/TRANSPORT TEMPERATURE – room temperature (18-25 degrees C)
UNACCEPTABLE CONDITIONS – alternate fixatives and decalcified specimens. Fixative duration should not exceed the fixed time
STABILITY – ambient: indefinitely, refrigerated: indefinitely
MRP – 7500.00
SPECIAL INSTRUCTIONS – clinical history is mandatory including surgical pathology reports
Clinical History is Mandatory.