GIST PDGFRA gene mutation

DESCRIPTION – a gastrointestinal stromal tumor is a type of cancer that begins in the digestive system. A GIST is a growth of cells that’s thought to form from a special type of nerve cells. These special nerve cells are in the walls of the digestive system

METHODOLOGY – next generation sequencing (NGS)

TURN AROUND TIME – 12 days

PATIENT PREPARATION –

COLLECT – tumor tissue

SPECIMEN PREPARATION – formalin fixed paraffin embedded tissue block. Protect the slides from excessive heat

STORAGE/TRANSPORT TEMPERATURE – room temperature or refrigerated

STABILITY – ambient: indefinitely; refrigerated: indefinitely

UNACCEPTABLE CONDITIONS – alternate fixative and decalcified specimen

SPECIAL INSTRUCTIONS – clinical history is mandatory