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E-cadherin

Description- E-cadherin is a type of cellular adhesion molecule and its absence is associated with invasive carcinoma. It differentiates lobular carcinoma in situ (LCIS) from ductal carcinoma in situ (DCIS) in indeterminate breast carcinoma and reduced expression in invasive bladder cancer and ductal carcinoma, no expression in lobular carcinoma and LCIS

 

Methodology: Immunohistochemistry

 

TAT: 3-5 days

 

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable

 

 

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