Description- Cytokeratin 20 is expressed in intestinal epithelium, gastric foveolar epithelium, some endocrine cells of the upper portions of the pyloric glands, urethelium, and Merkel cells in epidermis. This test aids in identifying colorectal carcinoma, adenomas of the gallbladder and bile ducts, ductal cell adenocarcinomas of the; pancreas, mucinous ovarian tumors, transitional-cell carcinomas, and Merkel-cell carcinomas of the skin Gastrointestinal adenocarcinomas .
TAT: 3-5 days
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable