t(4;14)(p16;q32) IGH/FGFR3

DESCRIPTION – the FGFR3 gene is located at 4p16.3 and IGH gene is located at 14q32. Approximately half of the multiple myeloma cases are associated with translocations involving IGH

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 7 days

PATEINT PREPARATION –

COLLECT – non diluted bone marrow aspirate or sodium heparin

SPECIMEN PREPARATION – 3-4 ml of bone marrow or peripheral blood in green top (sodium heparin) or lavender top (EDTA) tube

STORAGE/TRANSPORT TEMPERATURE – 2-8 degrees C (with cold pack) and transport within 72 hours

STABILITY – ambient: 48 hours; refrigerated: 48 hours

UNACCEPTABLE CONDITIONS – frozen and clotted specimens

MRP – 3500.00

SPECIAL INSTRUCTIONS – clinical history is mandatory