Cll Prognostic Pannel

DESCRIPTION – to aid in the diagnosis, lineage, assignment, sub-classification and response to treatment of hematologic malignancies

CLINICAL UTILITY – this test is used to detect prognostic important genetic abnormalities in CLL

COMPONENTS – del 6q, del 11q, del 13q, trisomy 12, del 17q

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 6 days

PATIENT PREPARATION –

COLLECT – non- diluted bone marrow aspirate or sodium heparin

SPECIMEN PREPARATION – 3-4 ml bone marrow or peripheral blood in lavender top (EDTA) or green top (sodium heparin)

STORAGE/TRANSPORT TEMPERATURE – room temperature

STABILITY – ambient: 48 hours; refrigerated: 48 hours

UNACCEPTABLE CONDITIONS – clotted specimens

MRP – 10000

SPECIAL INSTRUCTIONS – clinical history is mandatory including histopathological reports