Chromogranin A
Description- Chromogranin A is expressed in neuronal cells and in secretory granules of endocrine cells: parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas, and C cells of the thyroid. This test aids in identifying neuroendocrine tumors: pituitary adenomas, islet-cell tumors, phaeochromocytomas, medullary thyroid carcinomas, Merkel-cell tumors, and carcinoids
Methodology: Immunohistochemistry
TAT: 3-5 days
Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable

