What is the CD71 test?

The CD71 test is a laboratory test that measures the levels of transferrin receptor, which is also known as cluster of differentiation 71 (CD71). Transferrin receptor is a protein that is found on the surface of cells that require iron for growth and development, such as bone marrow cells. The CD71 test is often used as a marker for assessing the activity of bone marrow cells, as these cells require iron for the production of red blood cells. Abnormal levels of transferrin receptor may indicate various medical conditions, such as iron deficiency anemia, hemochromatosis, or certain types of cancer. The CD71 test is typically performed on a blood sample and is a useful tool for diagnosing and monitoring certain medical conditions.

How is the CD71 test performed?

The CD71 test is a laboratory test that measures the amount of transferrin receptor (CD71) on the surface of cells, typically red blood cells. The test is usually done using a blood sample collected from a vein in the arm. The blood sample is sent to a laboratory where it is analyzed to determine the level of CD71 on the surface of cells.

Before the test, the healthcare provider may ask the patient to fast for a certain period of time or avoid certain medications that may affect the test results. During the test, the healthcare provider will clean the site where the blood will be drawn and insert a needle into a vein to collect the blood sample. The process usually takes a few minutes and may cause some brief discomfort.

After the blood sample is collected, it is transported to a laboratory where it is analyzed using specialized equipment. The results of the test may be available within a few days, and the healthcare provider will discuss the results with the patient to determine if any further testing or treatment is necessary.

Overall, the CD71 test is a simple and non-invasive procedure that can provide important information about the level of transferrin receptor in the body, which is important for assessing iron status and other conditions related to bone marrow function.

What are the benefits of taking a CD71 test?

The CD71 test, also known as the transferrin receptor test, measures the levels of transferrin receptors in the blood. Transferrin receptors are proteins found on the surface of cells that bind to transferrin, a protein that carries iron in the bloodstream. The CD71 test helps in the diagnosis and management of various medical conditions, including anemia, iron deficiency, and bone marrow disorders.

One of the benefits of taking a CD71 test is that it can help in the early detection of anemia. Anemia is a condition in which the body does not have enough red blood cells to carry oxygen to the organs and tissues. The CD71 test measures the levels of transferrin receptors, which increase in response to low levels of iron in the body. When the body does not have enough iron to make hemoglobin, the protein that carries oxygen in the blood, it produces more transferrin receptors to increase its ability to absorb iron. Therefore, a high level of transferrin receptors in the blood is a sign of iron deficiency anemia.

Another benefit of the CD71 test is that it can help diagnose bone marrow disorders. The bone marrow is the spongy tissue inside the bones that produces blood cells, including red blood cells, white blood cells, and platelets. Disorders that affect the bone marrow can cause abnormal blood cell production, leading to conditions such as leukemia, lymphoma, and myelodysplastic syndromes. 

Are there any alternative tests to the CD71 test?

Yes, there are alternative tests to the CD71 test. Transferrin and transferrin receptor tests are also used to evaluate iron deficiency anemia. Transferrin is a protein that helps transport iron in the blood, and its levels can be measured to assess iron deficiency. Transferrin receptor levels can also be measured to evaluate the body's ability to absorb iron. In some cases, a bone marrow biopsy may also be performed to evaluate the production of red blood cells and identify any underlying conditions causing anemia. However, the CD71 test is still considered one of the most accurate and reliable tests for diagnosing iron deficiency anemia. It is always best to consult with a healthcare professional to determine the most appropriate testing method for an individual's specific case.

Are there any specific steps I need to take in order to prepare for the CD71 test in ?

Yes, there are some specific steps you need to take in order to prepare for the CD71 test in . Here are some of the things you need to keep in mind:

1. Consult with your doctor: It is important to consult with your doctor before taking any tests. Your doctor will give you specific instructions regarding any dietary restrictions or medications that you may need to avoid before the test.
2. Fasting: You may need to fast for a certain period of time before the test. It is important to follow the fasting instructions given by your doctor. This will help ensure accurate test results.
3. Drinking water: You may be asked to drink water before the test. This is to ensure that your body is properly hydrated, which can help with accurate test results.
4. Avoid strenuous exercise: Avoid any strenuous exercise or physical activity before the test. This can affect your test results.
5. Wear comfortable clothing: Wear comfortable clothing to the testing center. This will help you relax during the test.
6. Arrive early: Arrive early to the testing center to allow time for any paperwork or preparation that may be required.

By following these steps, you can ensure that you are properly prepared for the CD71 test in .

Description- CD71 is marker for erythroid components within bone marrow biopsies which aids in the determination of erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndrome

Methodology: Immunohistochemistry

TAT: 3-5 days

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable