Cytokine Profiling
& Protein Analysis
Precise, sensitive measurement of cytokines, chemokines, and soluble proteins to illuminate immune and inflammatory biology.
From single-analyte immunoassays to high-plex and ultrasensitive platforms, our cytokine and protein analysis services quantify the signaling molecules that drive immune response, inflammation, and therapeutic activity across research and clinical programs.
Reading the Language of the Immune System
Cytokines and chemokines are key signaling molecules that enable communication between immune cells. Their expression levels change rapidly in response to infection, inflammation, and therapeutic interventions, providing valuable insights into immune function and biological processes.
Because many of these mediators circulate at extremely low concentrations, accurate quantification demands carefully validated assays and the right analytical platform. Our team matches each project to the most appropriate method, balancing sensitivity, breadth, sample volume, and regulatory context to deliver dependable data.
- Quantify individual analytes or broad multiplex signatures from a single sample.
- Resolve low-abundance mediators with ultrasensitive detection technologies.
- Conserve precious specimens through low-volume, high-plex assays.
- Support exploratory research through regulated program requirements.
- Integrate seamlessly with immune monitoring and biomarker workflows.
Cytokine & Protein Analysis Capabilities
A flexible menu of immunoassay and proteomic services built to quantify the mediators that matter to your study.
Luminex
Bead-based multiplex immunoassays that quantify dozens of cytokines and proteins from a single low-volume sample with high throughput.
Olink Proteomics
Proximity extension assay technology delivering high-plex, highly specific protein measurement for deep proteomic profiling.
Meso Scale Discovery (MSD)
Electrochemiluminescence detection offering a wide dynamic range and low background for precise, sensitive analyte quantification.
ELISA
Validated single-analyte plate-based immunoassays for accurate, reproducible measurement of individual cytokines and soluble proteins.
Matched to Your
Analytes & Sensitivity
Solutions for Any Sensitivity or Multiplex Needs
| Feature | Luminex | Olink Proteomics | Meso Scale Discovery (MSD) | ELISA |
|---|---|---|---|---|
| Sensitivity | pg/mL | pg/mL | pg/mL | ng/mL – pg/mL |
| Dynamic Range | >4 logs | 3–4 logs | >4 logs | 2 logs |
| Multiplex Capabilities | 50–100 | 45/92 | 10 | 1 |
| Sample Volume | 50 µL | 1 µL | 25 µL | 50–100 µL |
| Best Use | Early Stages | All Stages | All Stages | All Stages |
Applications Across Research & Clinical Programs
Cytokine and protein data support discovery, safety, and translational goals across a wide range of therapeutic areas.
Immuno-Oncology
Track immune activation, cytokine release, and pharmacodynamic response to checkpoint inhibitors and cell therapies.
Autoimmune & Inflammation
Characterize inflammatory signatures to understand disease activity and monitor anti-inflammatory interventions.
Vaccine Development
Measure cytokine and antibody responses to evaluate immunogenicity across preclinical and clinical stages.
Cytokine Release Assessment
Quantify release profiles to support safety evaluation and cytokine release syndrome monitoring for biologics.
Infectious Disease
Profile host immune responses to pathogens to inform therapeutic and diagnostic research programs.
Biomarker Discovery
Identify and validate soluble protein biomarkers that stratify patients and predict therapeutic response.
Translational Research
Bridge mechanistic findings and clinical endpoints with harmonized, reproducible protein measurements.
Toxicology & Safety
Assess immune-mediated toxicity signals to support risk evaluation throughout development.
A Guided Analysis Workflow
From study consultation to secure data delivery, every step is tracked and quality-controlled.
Study Consultation
We align on analytes, matrix, sensitivity needs, and regulatory context to design the right assay strategy.
Sample Receipt & QC
Samples are logged, inspected, and quality-checked under controlled cold-chain conditions on arrival.
Assay Setup & Validation
Panels are configured and methods validated for accuracy, precision, and linearity ahead of sample testing.
Sample Analysis
Specimens are run on the selected platform with standards and controls to ensure reliable quantification.
Data Processing
Raw signals are curve-fit, normalized, and quality-reviewed by our scientific team for confident results.
Biostatistical Analysis
Concentration data is analyzed for trends, comparisons, and endpoint-relevant statistical interpretation.
Reporting
Findings are compiled into a clear, structured report with full traceability and methodology detail.
Secure Delivery
Results and datasets are delivered through encrypted, access-controlled channels for downstream use.
Why Choose CNC Path Lab
A trusted partner for cytokine and protein analysis projects of every scale.
Experienced Immunoassay Team
Scientists with deep expertise in cytokine, chemokine, and soluble protein measurement across study phases.
Multi-Platform Flexibility
Single-plex to high-plex and ultrasensitive platforms matched to your analytes and sensitivity requirements.
Rigorous Quality Standards
Validated methods and multi-stage checkpoints safeguard data integrity and reproducibility at every step.
Fit-for-Purpose Validation
Assays developed and qualified to match your study objectives and applicable regulatory expectations.
Secure Data Handling
Confidential management of samples and results across storage, transfer, and delivery.
Responsive Scientific Support
Guidance available from study design through execution and final reporting.
From Sample to Scientific Insight
Partner with a world-class precision diagnostics team
From biomarker discovery to AI-powered digital pathology, CNC Path Lab delivers rigorous, translational science that moves your program forward.
Life science innovators
come to CNC Path Lab
Ready to accelerate your clinical program? Our experts are here to help you design and execute the perfect laboratory strategy. Are you ready?