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CXCL13

Description- B-lymphocyte chemoattractant / B-cell attracting chemokine-1 (BLC/BCA-1); CXC chemokine family controlling the organization of B cells within follicles of lymphoid tissues such as spleen, lymph nodes, and Peyeru2019s patches; In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the Tcell.; CXCL is a useful marker in the diagnosis of angioimmunoblastic T-cell lymphoma; when used in a panel it can differentiate it from other proliferative T-cell lymphoma

Methodology: Immunohistochemistry

 

TAT: 3-5 days

 

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable

 

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