NABL | ICMR Accredited Lab | ICMR Reg. No.: CNCPLDD
powered by cancerncure.in | 7519071907
Logo

CD33

What is the purpose of the CD33 test?

The CD33 test is a diagnostic tool used to identify the presence of a protein called CD33 in the blood cells. This test is primarily used in the diagnosis of acute myeloid leukemia (AML), a type of blood and bone marrow cancer that is characterized by the rapid growth of abnormal white blood cells. CD33 is found on the surface of myeloid cells, which are the cells that give rise to red blood cells, platelets, and certain types of white blood cells. By measuring the amount of CD33 in a patient's blood, doctors can determine if they are at risk for developing AML or if they already have the disease. The CD33 test is also used to monitor the progress of AML treatment and to determine if a patient is in remission.

Who typically receives the CD33 test?

The CD33 test is typically received by patients who have been diagnosed with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). This test helps in determining the prognosis and treatment options for these patients by measuring the levels of CD33 protein on the surface of the cancer cells. CD33-targeted therapies, such as gemtuzumab ozogamicin, are also used in the treatment of AML and MDS patients who express high levels of CD33.

What are the results of the CD33 test?

The CD33 test is a diagnostic test that is used to detect the presence or absence of certain genetic mutations in the CD33 gene. These mutations are associated with an increased risk of developing acute myeloid leukemia (AML), a type of blood cancer.

The results of the CD33 test will indicate whether or not a person has a mutation in the CD33 gene. If a mutation is detected, the person may be at an increased risk of developing AML, and further testing and monitoring may be recommended.

It is important to note that a negative result does not necessarily mean that a person is not at risk for developing AML, as there may be other genetic mutations or risk factors that contribute to the development of the disease. Therefore, it is important for individuals to discuss their risk factors and testing options with their healthcare provider.

How is the CD33 test administered?

The CD33 test is typically administered through a blood sample. A healthcare professional will use a needle to draw blood from a vein in the arm, and the blood will be sent to a laboratory for testing. The laboratory will use specialized equipment to analyze the blood sample for the presence and levels of the CD33 protein. Depending on the results of the test, further diagnostic or treatment options may be recommended by a healthcare provider.In conclusion, the CD33 test is a valuable tool in diagnosing and monitoring the progress of acute myeloid leukemia and myelodysplastic syndrome. It helps healthcare providers determine the best treatment options for patients by measuring the levels of CD33 protein on the surface of cancer cells. While a negative result does not necessarily mean a person is not at risk for developing AML, the test can provide important information for patients and their healthcare providers to make informed decisions about their care. As research continues, the CD33 test has the potential to become even more integral in personalized cancer treatment.

What instructions should I follow before taking the CD33 test?

Before taking the CD33 test, it is important to follow some instructions to ensure accurate results. Here are some guidelines you should follow:

  1. Consult with your healthcare provider: It is important to consult with your healthcare provider before taking any tests. Your doctor will be able to advise you if the CD33 test is appropriate for you.
  2. Fasting: In some cases, fasting may be required before taking the CD33 test. Your healthcare provider will provide the necessary instructions if this is the case.
  3. Medications: Inform your healthcare provider of any medications you are currently taking, as they may affect the test results. Your doctor may advise you to stop or adjust the dosage of certain medications before taking the test.
  4. Sample collection: The CD33 test requires a blood sample. It is important to follow the instructions of the healthcare provider or the laboratory technician regarding the collection of the sample.
  5. Follow-up: Once the test results are available, follow up with your healthcare provider to discuss the results and any necessary next steps.

By following these instructions, you can ensure that the CD33 test provides accurate results, which can help in the diagnosis and treatment of certain medical conditions.

Are there any age restrictions for taking the CD33 test?

There are no age restrictions for taking the CD33 test. The test is a diagnostic tool used to detect the presence of the CD33 protein, which is associated with certain types of cancers. It can be performed on individuals of any age who are suspected of having CD33-positive cancer. However, it is important to note that depending on the specific type of cancer being tested for, there may be other factors that limit the usefulness of the CD33 test for certain age groups. It is always best to consult with a healthcare professional to determine the most appropriate diagnostic tests for an individual's specific situation.

Description- CD33 is expressed on the membrane and in the cytoplasm in early myeloid progenitor cells.

Methodology: Immunohistochemistry

TAT: 3-5 days

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable

 

Icon
Get Report In
Icon
Pre-Test Information
N/A
Home Collection-
Offer PriceN/A
Total AmountN/A
*inclusive of all the taxes, fees and subject to availability

Best Health Checkup Packages