Breast And Ovarian Cancer Panel

What is a breast and ovarian cancer panel test?

A breast and ovarian cancer panel test is a genetic test that examines a person's DNA for mutations or changes in specific genes that are associated with an increased risk of developing breast or ovarian cancer. The test analyzes genes such as BRCA1, BRCA2, PALB2, ATM, and CHEK2, among others.

The BRCA1 and BRCA2 genes are the most commonly associated genes with a higher risk of breast and ovarian cancer. Mutations in these genes can increase a person's risk of developing breast cancer up to 80% and ovarian cancer up to 44%.

Other genes that are analyzed in the panel test have a lower risk, but still contribute to a person's likelihood of developing cancer. These genes include PALB2, which increases the risk of breast cancer in women, and ATM and CHEK2, which increase the risk of both breast and ovarian cancer.

The test is usually recommended for people who have a family history of breast or ovarian cancer, especially if cancer has occurred in multiple family members or at a young age. It can also be recommended for individuals who have been diagnosed with cancer at a young age or have had multiple cancers.

The test is typically performed through a blood or saliva sample, which is sent to a laboratory for analysis. The results of the test can be used to assess a person's risk of developing breast or ovarian cancer and can guide decisions about medical management, such as increased surveillance, preventative surgery, or targeted therapies.

Itis important to note that a breast and ovarian cancer panel test is not a definitive diagnosis of cancer. It is a tool to assess a person's risk and guide medical management decisions. It is also important to understand that not all mutations in these genes result in cancer and that other factors, such as environmental and lifestyle factors, can also contribute to a person's risk of developing cancer.

If you are considering a breast and ovarian cancer panel test, it is important to discuss the test with a healthcare professional who can provide genetic counseling and help you understand the implications of the results. They can also help you make informed decisions about medical management and provide support throughout the testing process. With this information, individuals can take proactive steps to manage their risk and potentially prevent the development of breast or ovarian cancer.

How much does a breast and ovarian cancer panel test typically cost?

Breast and ovarian cancer panel tests are a type of genetic testing that can help identify genetic mutations associated with an increased risk for developing these types of cancer. The cost of such tests can vary depending on the laboratory and location, so it's difficult to provide an exact figure for . However, we can give you a general idea of what to expect.

On average, a breast and ovarian cancer panel test can cost between Rs. 15,000 to Rs. 20,000 in . However, the cost can vary depending on several factors such as the laboratory, the type of test, and additional services that may be required. Some laboratories may also offer different packages that include multiple genetic tests, which can affect the overall cost.

It's important to note that many insurance companies cover the cost of genetic testing for individuals with a strong family history of breast and ovarian cancer. If you have a family history of these types of cancer, you may want to check with your insurance provider to see if they cover the cost of testing.

In summary, the cost of a breast and ovarian cancer panel test in typically ranges between Rs. 700 to Rs. 1000. However, it's important to check with your insurance provider to see if they cover the cost of testing if you have a family history of these types of cancer.

How long does it take to get the results of a breast and ovarian cancer panel test in ?

If you're living in and have undergone a breast and ovarian cancer panel test, you're probably wondering how long it takes to receive the results. The waiting time for results can be stressful and nerve-wracking, especially when dealing with a serious illness like cancer.

The breast and ovarian cancer panel test is a type of genetic testing that examines specific genes associated with these types of cancer. The test involves collecting a blood sample and analyzing it in a laboratory. The laboratory will look for mutations or changes in specific genes known to increase the risk of developing breast or ovarian cancer.

The time it takes to receive the results of the test can vary depending on the laboratory where the test is conducted. In , there are a number of reputable laboratories that offer this type of testing. Generally, you can expect to receive your results the next day from the date of your test. However, some laboratories may provide results in a shorter or longer period of time depending on their workload and testing procedures.

It's important to note that while waiting for your results, it's normal to experience anxiety or worry. It's essential to take care of your mental and emotional health as it can be challenging to deal with the uncertainty of not knowing. Consider speaking with a healthcare professional or a counselor to help manage your emotions during this time.

In summary, if you have undergone a breast and ovarian cancer panel test in , expect to receive your results next day of your test. However, this waiting period may vary depending on the laboratory conducting the test. While waiting for your results, taking care of your mental and emotional well-being is crucial, especially if you're dealing with a family history of cancer. Seeking support from a healthcare professional or a counselor can help you manage your anxiety and worry.

It's also important to understand that genetic testing is not a substitute for regular cancer screenings and check-ups. Even if you receive a negative result, it's still important to continue with routine cancer screenings as recommended by your healthcare provider. Early detection and treatment are crucial in improving the chances of successful treatment and recovery. By understanding the cost and waiting time for a breast and ovarian cancer panel test, you can make an informed decision about whether to undergo testing based on your personal risk factors and family history.

What types of doctors are qualified to perform a breast and ovarian cancer panel test in ?

The breast and ovarian cancer panel test is a highly specialized diagnostic tool that helps in the detection of genetic mutations associated with breast and ovarian cancer. In , there are several types of doctors who are qualified to perform this test.

1. Medical Oncologists: Medical oncologists are doctors who specialize in the diagnosis and treatment of cancer. They are trained to perform genetic tests and interpret the results. They work closely with genetic counselors to provide personalized treatment plans based on the patient's genetic makeup.

2. Gynecologic Oncologists: Gynecologic oncologists are doctors who specialize in the diagnosis and treatment of cancers that affect the female reproductive system. They can perform a breast and ovarian cancer panel test and use the results to develop a treatment plan that is specific to the patient's needs.

3. Surgical Oncologists: Surgical oncologists are doctors who specialize in the surgical treatment of cancer. They can perform biopsies to collect tissue samples for testing and can also perform prophylactic surgeries to reduce the risk of developing breast and ovarian cancer in patients with a high genetic risk.

4. Genetic Counselors: Genetic counselors are healthcare professionals who specialize in the interpretation of genetic test results. They work closely with doctors to provide patients with personalized counseling and support based on their genetic makeup.

It is important to choose a qualified doctor who has experience in performing breast and ovarian cancer panel tests. Patients should always consult with their healthcare provider to determine which doctor is best suited to perform the test and develop a personalized treatment plan based on their individual needs. Additionally, patients should also consider the cost and waiting time for the test, as it can vary depending on the healthcare provider and location.

In , there are several healthcare facilities that offer breast and ovarian cancer panel testing, including government and private hospitals, diagnostic centers, and specialized cancer treatment centers. Patients should research and compare the cost and waiting time for the test at different facilities to make an informed decision. Some healthcare providers also offer financial assistance or insurance coverage for the test, which can help reduce the cost for patients.

Overall, undergoing a breast and ovarian cancer panel test can provide valuable information about a patient's genetic risk for these types of cancers. By choosing a qualified doctor and considering the cost and waiting time, patients can make an informed decision about whether to undergo testing and take proactive steps to manage their health. It is always recommended to consult with a healthcare provider to determine the best course of action for each individual patient.

Breast and Ovarian Cancer can be diagnosed through several tests:

Breast Cancer Tests:

1. Mammogram: This is an X-ray of the breast that can detect changes in breast tissue, including lumps that may be cancerous.
2. Breast ultrasound: This test uses sound waves to create images of the breast tissue and can help to determine whether a lump is solid or fluid-filled.
3. Breast MRI: This test uses a magnetic field and radio waves to create images of the breast tissue and can help to detect abnormalities that may not be visible on a mammogram or ultrasound.
4. Biopsy: This involves removing a small sample of breast tissue for examination under a microscope to determine if cancer cells are present.

Ovarian Cancer Tests:

1. Pelvic exam: This involves a physical examination of the pelvic area to detect any abnormalities or swelling.
2. Transvaginal ultrasound: This test uses sound waves to create images of the ovaries and can help to detect any cysts or masses that may be cancerous.
3. CA-125 blood test: This test measures the level of a protein called CA-125 in the blood. Elevated levels of CA-125 may indicate ovarian cancer, but this test is not specific to ovarian cancer and may be elevated for other reasons.
4. Biopsy: This involves removing a small sample of tissue from the ovary for examination under a microscope to determine if cancer cells are present.

It's important to note that not all screening tests are appropriate for everyone, and some tests may be more accurate than others. Your healthcare provider can help to determine which tests are appropriate for you based on your individual risk factors and medical history.

Breast And Ovarian Cancer Symptoms:

Breast Cancer Symptoms:

1. A lump or thickening in the breast or under the armpit.
2. A change in the size or shape of the breast.
3. Pain or tenderness in the breast or nipple.
4. Nipple discharge other than breast milk.
5. Swelling or redness in the breast or nipple.
6. A change in the skin texture or appearance, such as dimpling, puckering or scaling.
7. An indentation or flattening of the breast.
8. A rash or crusting of the nipple or surrounding area.
9. A change in the position of the nipple.
10. Breast pain that is new or persistent.

Ovarian Cancer Symptoms:

1. Abdominal bloating, swelling, or fullness.
2. Pelvic pain or pressure.
3. Difficulty eating or feeling full quickly.
4. Changes in bowel or bladder habits, such as constipation or frequent urination.
5. Nausea or vomiting.
6. Fatigue or weakness.
7. Unexplained weight loss or gain.
8. Abnormal vaginal bleeding.
9. Back pain.
10. Pain during sex.

It's important to note that these symptoms can be caused by a variety of conditions, and having one or more of these symptoms does not necessarily mean that a person has breast or silent signs ovarian cancer. However, if you are experiencing any of these symptoms, it's important to talk to your healthcare provider to determine the cause and receive appropriate treatment.
 

DESCRIPTION – the breast and ovarian cancer comprehensive panel examines 25 genes associated with an increased risk for hereditary breast cancer and hereditary ovarian cancer

METHODOLOGY – next generation sequencing (NGS)

TURN-AROUND TIME – 3-6 weeks

PATIENT PREPARATION –

COLLECT – lavender (EDTA) or yellow (ACD solution A or B)

SPECIMEN PREPARATION – transport 3 ml whole blood

STORAGE/TRANSPORT TEMPERATURE – refrigerated

STABILITY – ambient: 1 week; refrigerated: 1 month

SPECIAL INSTRUCTIONS – clinical history is mandatory